Sodium Inactivation in Nerve Fibers

Effects of Changes in Ionic Strength on Inactivation and Threshold in Perfused Nerve Fibers of Loligo

There is now general agreement that dilution of the internal potassium solution with a non-electrolyte shifts the threshold and the inactivation curve in the direction of a more positive internal potential (1-5). At first it was not clear whether the shift was due to dilution of potassium or to a change of ionic strength. Baker et al. (3) considered that the second alternative was more likely, ...

The Role of Capsaicin-induced Acute Inactivation of C-fibers on Tactile Learning in Rat

Myelinated retinal nerve fibers

A 7-year-old girl of second degree consanguineous parents, presented with an 8 months history of intermittent exotropia of the left eye. Cycloplegic refraction was -0.25.-0.50×165o and -3.00.0.50×20o in the right and left eyes respectively. An initial objective assessment of the visual function showed a best corrected visual acuity of 12/10 in the right eye and 6/10 in the left eye. Fundoscopy ...

Olfactory Nerve Fibers

Cross sections of olfactory nerves present a unique appearance. They indicate the presence of large numbers of very small nerve fibers, with a modal diameter of about 0.2 micro and a narrow range for their size variation. From one side of the nasal septum of a pig the yield of fibers was estimated at 6,000,000; the number arising from the turbinates would be considerably larger. The fibers are ...

Slow Sodium Inactivation in Nerve After Exposure to Sulfhydryl Blocking Reagents

I N T R O D U C T I O N T h e b i o c h e m i c a l c o m p o n e n t s o f exc i t ab le m e m b r a n e s tha t a r e a s soc i a t ed wi th t he c o n t r o l o f ionic c o n d u c t a n c e a r e n o t ye t well c h a r a c t e r i z e d . T h e r e is s o m e e v i d e n c e t ha t m e m b r a n e p r o t e i n s a r e i nvo lved in t he g a t i n g o f ionic c u r r e n t s , b o t h f r ...